Source: GWASDB

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs76418789
rs76418789
IL23R ; C1orf141
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.850 GeneticVariation GWASDB Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations. 23850713

2014
dbSNP: rs9271366
rs9271366
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		A 0.820 GeneticVariation GWASDB Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations. 23850713

2014
dbSNP: rs6856616
rs6856616
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		C 0.810 GeneticVariation GWASDB We identified three new susceptibility loci at genome-wide significance: rs6856616 at 4p14 (OR=1.43, combined p=3.60×10(-14)), rs11195128 at 10q25 (OR=1.42, combined p=1.55×10(-10)) and rs11235667 at 11q13 (OR=1.46, combined p=7.15×10(-9)), implicating ATG16L2 and/or FCHSD2 as novel susceptibility genes for CD. 23850713

2014
dbSNP: rs11235667
rs11235667
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.810 GeneticVariation GWASDB Further analysis of the 11q13 locus revealed a non-synonymous single nucleotide polymorphism (SNP) (R220W/rs11235604) in the evolutionarily conserved region of ATG16L2 with stronger association (OR=1.61, combined p=2.44×10(-12)) than rs11235667, suggesting ATG16L2 as a novel susceptibility gene for CD and rs11235604 to be a potential causal variant of the association. 23850713

2014
dbSNP: rs11195128
rs11195128
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.810 GeneticVariation GWASDB We identified three new susceptibility loci at genome-wide significance: rs6856616 at 4p14 (OR=1.43, combined p=3.60×10(-14)), rs11195128 at 10q25 (OR=1.42, combined p=1.55×10(-10)) and rs11235667 at 11q13 (OR=1.46, combined p=7.15×10(-9)), implicating ATG16L2 and/or FCHSD2 as novel susceptibility genes for CD. 23850713

2014
dbSNP: rs751728
rs751728
MLN ; LEMD2 ; LOC105375024
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.800 GeneticVariation GWASDB Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations. 23850713

2014
dbSNP: rs2149085
rs2149085
RNASET2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.800 GeneticVariation GWASDB Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations. 23850713

2014
dbSNP: rs10947261
rs10947261
BTNL2 ; TSBP1-AS1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.800 GeneticVariation GWASDB Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations. 23850713

2014
dbSNP: rs11235604
rs11235604
ATG16L2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.730 GeneticVariation GWASDB Further analysis of the 11q13 locus revealed a non-synonymous single nucleotide polymorphism (SNP) (R220W/rs11235604) in the evolutionarily conserved region of ATG16L2 with stronger association (OR=1.61, combined p=2.44×10(-12)) than rs11235667, suggesting ATG16L2 as a novel susceptibility gene for CD and rs11235604 to be a potential causal variant of the association. 23850713

2014
dbSNP: rs394522
rs394522
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		C 0.700 GeneticVariation GWASDB Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations. 23850713

2014
dbSNP: rs11209026
rs11209026
IL23R
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.900 GeneticVariation GWASDB A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300. 22936669

2013
dbSNP: rs6478109
rs6478109
TNFSF15
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.830 GeneticVariation GWASDB A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. 23266558

2013
dbSNP: rs2076756
rs2076756
NOD2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.830 GeneticVariation GWASDB A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300. 22936669

2013
dbSNP: rs9271366
rs9271366
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.820 GeneticVariation GWASDB A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. 23266558

2013
dbSNP: rs6478106
rs6478106
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.820 GeneticVariation GWASDB We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)). 23266558

2013
dbSNP: rs9891119
rs9891119
STAT3
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		A 0.810 GeneticVariation GWASDB We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)). 23266558

2013
dbSNP: rs7765379
rs7765379
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.810 GeneticVariation GWASDB We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)). 23266558

2013
dbSNP: rs9267911
rs9267911
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.800 GeneticVariation GWASDB A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. 23266558

2013
dbSNP: rs7329174
rs7329174
ELF1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.800 GeneticVariation GWASDB A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. 23266558

2013
dbSNP: rs72981516
rs72981516
FCHSD2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.800 GeneticVariation GWASDB A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. 23266558

2013
dbSNP: rs4820425
rs4820425
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		A 0.800 GeneticVariation GWASDB A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300. 22936669

2013
dbSNP: rs3792109
rs3792109
ATG16L1 ; SCARNA5
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		A 0.800 GeneticVariation GWASDB A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300. 22936669

2013
dbSNP: rs3094188
rs3094188
POU5F1 ; PSORS1C3
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		C 0.800 GeneticVariation GWASDB A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. 23266558

2013
dbSNP: rs2834215
rs2834215
IFNGR2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.800 GeneticVariation GWASDB A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300. 22936669

2013
dbSNP: rs2006996
rs2006996
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.800 GeneticVariation GWASDB A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. 23266558

2013